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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
drug:
Phospholipids
Research Papers that Mention the Interaction
“Prior binding of phospholipids to factor V prevents inhibition by EDTA.”
Bovine factor v: a calcium-containing metalloprotein.“In this issue, Bonomini et al. [3] confirm a highly significant increase in the exposure of negatively charged phospholipids by platelets isolated from EDTA anticoagulated uremic blood [4].”
“The addition of EDTA to the incubation mixture results in inhibition of the conversion of serine to phospholipid , with the result that 3-keto-dihydro-sphingosine is the sole product.”
Sphingolipid metabolism II. The biosynthesis of 3-keto-dihydrosphingosine by a partially-purified enzyme from rat brain“ EDTA , known to inhibit phospholipase A by Ca 2+ sequestration, was found to suppress in a parallel manner both the phospholipid splitting and the swelling activity of the enzyme preparation.”
“It is attributed to EDTA induced alteration of surface glycoproteins (GP) and anionic phospholipids , which enables binding of antiplatelet antibodies, which in turn cause agglutination.”
Ethylenediaminetetraacetic Acid (EDTA) - dependent pseudothrombocytopenia: a case report.“The addition of EDTA and α-tocopherol, which were mainly employed with the aim to suppress oxidation processes, also reduced the phospholipid hydrolysis to a certain extent.”
“ EDTA-Tris treatment appeared to progressively strip phospholipids from the cells that were synthesized at progressively later times.”
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