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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
drug:
Nitrendipine
Research Papers that Mention the Interaction
“ Nitrendipine binding in the presence of EDTA significantly decreased to 419 +/- 42 fmol/mg protein (P less than 0.001) which equates to 42.0% of control.”
Effect of divalent cation chelation on dihydropyridine binding in isolated cardiac sarcolemma vesicles.“ EDTA , ATP, and La3+, which are known to reduce high affinity nitrendipine binding, also inhibited the photoaffinity labeling of this membrane protein by [3H]nitrendipine.”
“Treatment of ileal and aortic smooth muscle and cardiac muscle with EDTA reduced specific [3H]nitrendipine binding by 70 to 95%.”
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