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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
drug:
Nifedipine
Research Papers that Mention the Interaction
“Pretreatment with nifedipine (a calcium channel blocker) or extracellular Ca+2 removal by ethylenediaminetetraacetic acid ( EDTA ) greatly attenuated the relaxation effect, suggesting that calcium ion might be involved.”
In vitro relaxation of rabbit and human internal anal sphincter by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa.“L-1-induced transient contraction was also decreased (P < 0.05), 3) in Ca2+ free edetic acid medium , in the presence of nifedipine 10 micromol .”
Contractile responses of diabetic rat aorta to phenylephrine at different stages of diabetic duration.“This rapid increase in [Ca2+]i was blocked by addition of EDTA (2 mM) to the external medium or by pretreatment of the cells with the calcium channel antagonist nifedipine (10 microM).”
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