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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Edetic Acid
supplement:
NAD
Research Papers that Mention the Interaction
“Divalent cations, preferentially Zn2+ and Mn2+, were required for the pyrophosphatase activity, since in the presence of the Zn2+ chelator TPEN (N,N,N',N'-tetrakis(2-pyridyl-methyl)ethylenediamine) or EDTA , the NAD degradation was inhibited by about 50%.”
Modulatory role of GTP-binding proteins in the endogenous ADP-ribosylation of cytosolic proteins.“Inhibition of mitochondrial enzyme systems is largely prevented by added DPN , and, to a lesser degree, by EDTA.”
“Recently it was shown that incubation of rat brush-border membrane with NAD+ resulted in release of Pi which was prevented by EDTA.”
NAD+-induced inhibition of phosphate transport in canine renal brush-border membranes. Mediation through a process other than or in addition to NAD+ hydrolysis.“ EDTA , which prevents the release of Pi from NAD+ and which itself has no direct effect on brush-border membrane Pi transport, reverses the NAD+ inhibition of Na+-dependent Pi transport.”
“ NAD+ (and NADPH) activity is only slightly changed by EDTA.”
Glutamate dehydrogenase from pea roots: purification and properties of the enzyme.
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