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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
drug:
Methyl Isocyanate
Research Papers that Mention the Interaction
“An MBL Etest (bioMérieux) revealed a 24-fold reduction of imipenem MIC when combined with EDTA , which suggested production of an MBL.”
“The adhesion process and also formation of the biofilm was inhibited by EDTA at concentrations 1.0-2.0 mmol/l (2-8 x MIC).”
“The isolate was resistant to all antibiotics except amikacin, and displayed an imipenem MIC of 64 mg/L that decreased to 8 mg/L in the presence of EDTA.”
“The data obtained showed that in 73 strains (52.9%) was a significant correlation between the specific enzyme activity and resistance, however in 38 strains (27.5%) an essential role was played by permeability barrier because the addition of subinhibitory levels of EDTA produced markedly reduction in the MIC.”
[The role of beta-lactamases and the permeability barrier in resistance to beta-lactam antibiotics].“ EDTA could reduce MIC for E. coli and P. aeruginosa.”
Nonselective Mevalonate Kinase Inhibitor as a Novel Class of Antibacterial Agents“Against E. coli NCTC 11560, an eightfold decrease in MIC and minimum bactericidal concentration (MBC) was recorded when tested in the presence of EDTA.”
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