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Last Updated: 2 years ago

Possible Interaction: Edetic Acid and Methionine

supplement:

Edetic Acid

supplement:

Methionine

Research Papers that Mention the Interaction

Preparation of the liver enzyme in the absence of EDTA did not yield a predominantly M form of the enzyme, and incubation of the M form in the presence of EDTA did not convert it into the L form, but resulted in inhibition of enzyme activity.
The Biochemical journal  •  1973  |  View Paper
The enzyme was completely inhibited in the same system by 5 × 10 −4 M EDTA.
Biochemical pharmacology  •  1972  |  View Paper
The more exposed the methionine residue is, the more difficult it is to be protected by EDTA.
Pharmaceutical Research  •  2004  |  View Paper
Addition of EDTA at a concentration of 5 × 10−3 M caused an inhibition of about 50%, however a complete inhibition for enzyme activity was obtained at 10−2 M EDTA.
Journal of basic microbiology  •  2003  |  View Paper
Methionine production by both transmethylase was progressively inhibited by additions of 2-mercaptoethanol and by the presence of EDTA.
Biochimica et biophysica acta  •  1970  |  View Paper
The formation of methionine is inhibited by high ionic strength, ethylenediamine tetraacetic acid , and the folate substrate analogues pteroyl-α-glutamylglutamic acid, pteroyl-γ-glutamyl-γ-glutamylglutamic acid, and 5-methyltetrahydropteroyl-α-glutamylglutamate.
The Journal of biological chemistry  •  1970  |  View Paper
In the absence of Ca ++ , EDTA begins to accelerate the dephosphorylation rate at about 10 −4 M and achieves a maximum acceleration of approximately 400% at about 10 −2 M .
Archives of biochemistry and biophysics  •  1954  |  View Paper