Possible Interaction: Edetic Acid and Magnesium Chloride

“The degree of EDTA activation of both enzymes decreased with increasing MgCl2 concentration.”

“ MgCl2 will completely reverse the inhibition caused by EDTA and promote subunit association.”

“Moreover, the addition of 20 mM MgCl2 restored tail degradation blocked by EDTA.”

“Activity is eliminated by EDTA at a concentration of <1 mM, even in the presence of 4 mM MgCl2 , suggesting that the three-dimensional conformation of the RNA should be maintained for this activity.”

“Both ara‐chidonoyl‐CoA and palmitoyl‐CoA synthesis activities showed an absolute requirement for ATP and CoA. This activity was strongly enhanced by magnesium chloride and inhibited by EDTA.”

“The Kd values for ADP and ATP in the presence of EDTA were 0.6 mM and 3.7 mM, respectively; MgCl2 decreased the Kd values to 0.1 mM for both ADP and ATP.”

“This degradation was most rapid in the presence of EDTA , and was inhibited by MgCl2 and CaCl2.”

“ MgCl2 effectively replaced CaCl2 as a stabilizing agent at 25 degrees C if added with 5 mM EDTA.”

“Sucrose density gradient analysis (in low salt) revealed that CaCl2 plus EDTA enhanced the steroid-receptor complex sedimentation coefficient from 7 S to … S. Unlike molybdate, CaCl2 plus EDTA had no apparent effect on steroid-receptor complex thermal transformation into a nuclear binding form, while MgCl2 … EDTA partially … transformation.”

“It is inhibited by EDTA and activated by MgCl2.”

“It has been shown that addition of 1 mM EDTA and 5 mM MgCl2 accelerates the aggregation process.”