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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Edetic Acid and Gentamicin

supplement:

Edetic Acid

Research Papers that Mention the Interaction

Indifference to additive activity was observed for tested combinations and MIC value of cefotaxime or gentamicin in combination with EDTA was less than antibiotic alone in the most tested isolates.
Microbial pathogenesis  •  2021  |  View Paper
Gentamicin uptake was also significantly reduced in the presence of the megalin inhibitors RAP and EDTA suggesting that megalin is likely involved in gentamicin uptake.
The AAPS Journal  •  2015  |  View Paper
In the presence of EDTA and sodium citrate susceptibility of the strain to gentamicin and rifampicin increased markedly.
Folia Microbiologica  •  2008  |  View Paper
Furthermore, a combination of EDTA and gentamicin results in complete killing of biofilm cells.
Applied and Environmental Microbiology  •  2006  |  View Paper
EDTA and gentamicin showed marked synergy in both 'killing curve' and PAE experiments.
The Journal of antimicrobial chemotherapy  •  1990  |  View Paper