Possible Interaction: Edetic Acid and Ferrous

“Peroxidation of liposomes in the presence of Al(III) and Fe(II) salts is inhibited by the chelating agent desferrioxamine, and by EDTA and diethylenetriaminepentaacetic acid at concentrations greater than those of Fe(II) salt.”

“The addition to membranes of ferrous iron and EDTA in an approximately 1:1 ratio resulted in conversion to the ferric iron form in several minutes.”

“Addition of ethylenediaminetetraacetic acid (EDTA) inhibits both LPO and protein oxidative modifications induced by Al(III) and Fe(II) ions.”

“DTPA (diethylenetriamine pentaacetic acid), EDTA , and EGTA protected against lipid peroxidation by Fe+2 and allowed almost complete regeneration of rhodopsin.”

“The presence of EDTA or nitrilotriacetic acid significantly inhibits both Fe(II) formation and phenanthrene photodegradation because these organic anions tend to chelate with Fe(III), leading to decreases in the electron-accepting potential of Fe(III)-smectite and a weakened interaction between phenanthrene and Fe(III)-smectite.”

“On the other hand, Fe2+ ( EDTA ) greatly augmented both ascorbate autoxidation and ascorbate-dependent .OH production.”

“The stability of HPAs decreases with increasing pH or increasing temperature, while added Fe(II ) in the presence and absence of EDTA accelerates H2O2 and HPA decomposition.”