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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
supplement:
Cd2+
Research Papers that Mention the Interaction
“ EDTA inactivates the enzyme, and enzyme activity is restored by several divalent metal ions including (in order of decreasing effectiveness) Cd2+ , Co2+, Zn2+, and Mn2+.”
Expression, Purification, and Characterisation of Dehydroquinate Synthase from Pyrococcus furiosus“ EDTA inactivates the enzyme and enzyme activity is restored by a wide range of divalent metal ions including (in order of decreasing effectiveness): Zn2+, Cd2+ , Mn2+, Co2+, Ni2+, Ca2+, Hg2+, and Cu2+.”
“The effects ranged from total inhibition of Cd2+ and Pb2+ uptake at equimolar concentrations of EDTA to no change in uptake of La3+ or UO 2+2 at 12‐fold molar excesses of Cl− or CO 2−3 .”
“The inhibition by EDTA and Zincon is reversed specifically by Zn2+ while the inhibition by EDTA is prevented by Zn2+ and Mn2+ and to, a minor extent, by Cd2+.”
“The polymerization … by ethylenediaminetetraacetic acid could not be reversed by the addition of Mg2+, Sr2+ or Ba2+, whose stability constants are smaller … that of Ca2+, but it could be completely reversed, and even directly accelerated by Zn2+, Cu2+, Cd2+ or Co2+ whose stability constants … greater than that of Ca2+.”
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