“ Econazole (0.1, 1 and 10 microM) significantly inhibited receptor-operated (phenylephrine, Phe ) and depolarization (KCl)-induced contractions of endothelium-intact or -denuded rings in a noncompetitive and concentration-dependent manner.”
“ Econazole caused a biphasic response in precontracted by Phe or KCl in endothelium-intact and -denuded rings, first a transient contraction following sustained relaxation.”