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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Econazole and Epinephrine

supplement:

Epinephrine

Research Papers that Mention the Interaction

The imidazole antifungal drugs econazole and miconazole have previously been shown to disrupt steroidogenesis in Leydig and adrenal cells by inhibiting 17alpha-hydroxylase/17,20-lyase (P450c17) enzyme activity, thus reducing the conversion of progesterone to androstenedione.
The Journal of Steroid Biochemistry and Molecular Biology  •  2000  |  View Paper