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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Econazole
supplement:
Epinephrine
Research Papers that Mention the Interaction
“The imidazole antifungal drugs econazole and miconazole have previously been shown to disrupt steroidogenesis in Leydig and adrenal cells by inhibiting 17alpha-hydroxylase/17,20-lyase (P450c17) enzyme activity, thus reducing the conversion of progesterone to androstenedione.”
Econazole and miconazole inhibit steroidogenesis and disrupt steroidogenic acute regulatory (StAR) protein expression post-transcriptionally
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