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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Ebselen
drug:
Thrombin Alfa
Research Papers that Mention the Interaction
“ Ebselen … recombinant human IDO (rIDO) with an apparent inhibition constant of 94 +/- 17 nM. Optical and resonance Raman spectroscopy showed that ebselen altered the active site heme … by lowering the vibrational frequency of the Fe-CO stretch of the CO complex, indicating an opening of the distal heme pocket.”
The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues.
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