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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Doxycycline
supplement:
Glutathione
Research Papers that Mention the Interaction
“Furthermore, the antioxidant impact of doxycycline was evidenced by the significant elevation in glutathione level and depressing MDA level.”
Hepatoprotective and anti-tumor effects of targeting MMP-9 in hepatocellular carcinoma and its relation to vascular invasion markers“ DOXY caused a marked increase in the hippocampal expression of phospho-CREB and GSH concentrations.”
Doxycycline at subantimicrobial dose combined with escitalopram reverses depressive-like behavior and neuroinflammatory hippocampal alterations in the lipopolysaccharide model of depression.“ DOX significantly increased glutathione , superoxide dismutase and catalase levels in the brain of chronic KET-treated mice.”
“Glutathione levels significantly decreased after ischemia/reperfusion injury when compared with the control group and doxycycline pretreatment significantly increased glutathione levels when compared with the ischemia/reperfusion group.”
“We have generated dopaminergic PC12 cell lines in which levels of GSH can be inducibly down-regulated via doxycycline induction of antisense messages against both the heavy and light subunits of γ-glutamyl-cysteine synthetase, the rate-limiting enzyme in glutathione synthesis.”
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