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Last Updated: 3 years ago

Possible Interaction: Doxycycline and Bovine Cartilage

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drug:

Doxycycline

supplement:

Bovine Cartilage

Research Papers that Mention the Interaction

“On SDS-PAGE, the cleavage products generated by cartilage extracts were larger and less abundant, indicating less complete cleavage, when doxycycline (10 or 30 microM) was added to the samples.”

Doxycycline inhibits type XI collagenolytic activity of extracts from human osteoarthritic cartilage and of gelatinase.

The Journal of rheumatology • 1991 | View Paper

“RESULTS Five days of do ycycline tr eatment, in a dose of either 100 mg bid or 100 mg qam, inhibited gelatinase activity in the car tilage extracts (p = 0.003, 0.008, respectively).”

Oral administration of doxycycline reduces collagenase and gelatinase activities in extracts of human osteoarthritic cartilage.

The Journal of rheumatology • 1998 | View Paper

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