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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Doxorubicin Hydrochloride and Tocotrienols

Research Papers that Mention the Interaction

In addition, increasing lines of evidence has shown that tocotrienols can sensitize cancer cells to chemotherapeutic agents such as celecoxib, doxorubicin , erlotinib, gefitinib, gemcitabine, paclitaxel, statin etc.
Pharmacological research  •  2018  |  View Paper
In addition, γ-tocotrienol actively inhibited the expression of P-gp and increased the accumulation of doxorubicin in cells, which led to the enhanced G2/M arrest and cell apoptosis.
The Journal of Steroid Biochemistry and Molecular Biology  •  2017  |  View Paper
Alpha- and gamma-tocotrienols had inhibitory effects on lipid peroxidation of murine microsomes by adriamycin.
Chemical & pharmaceutical bulletin  •  1989  |  View Paper