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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Ferric Ion
Research Papers that Mention the Interaction
“In the presence of Fe(III) , NADH dehydrogenase-catalyzed reduction of doxorubicin caused enhancement in the content of all modified bases over control levels.”
DNA base modifications induced in isolated human chromatin by NADH dehydrogenase-catalyzed reduction of doxorubicin.“These results suggest that ADR interferes with the calcium accumulation activity of the SR and that ferric iron potentiates this effect.”
Inhibition of calcium accumulation by the sarcoplasmic reticulum: a putative mechanism for the cardiotoxicity of adriamycin.“In the presence of ferric ions, doxorubicin forms a complex which self-reduces the iron moiety to form a ferrous complex.”
“In the presence of Fe(III) the one-electron reduction potentials shifted toward positive values by 0.16 and 0.1 V for Qbc and adriamycin , respectively.”
Role of quinone-iron(III) interaction in NADPH-dependent enzymatic generation of hydroxyl radicals.
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