supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Docosahexaenoic Acid
Research Papers that Mention the Interaction
“ DHA improved the inhibitory effect of doxorubicin on proliferation and invasion of MCF-7dox cells.”
DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA“Addition of doxorubicin to DHA further increased the glutathione level, indicative of the generation of an oxidative stress.”
“ DHA elicited by itself a 3.7-fold malondialdehyde level increase, additive to that induced by doxorubicin.”
“In MDA-MB-231, doxorubicin efficacy enhancement by DHA was linked to an increase in malondialdehyde level, a final product of lipid peroxidation.”
“Among all polyunsaturated fatty acids tested, docosahexaenoic acid DHA , 22:6n‐3) was the most potent in increasing doxorubicin cytotoxicity: cell viability decreased from 54% in the presence of 10−7 M doxorubicin alone to 21% when cells were incubated with doxorubicin and DHA.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback