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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Doxorubicin Hydrochloride and Acetylcysteine Amide

Research Papers that Mention the Interaction

CONCLUSIONS NA A at tenuated the cardiotoxic side effects of DOX + TRZ in a murine model of chemotherapy-induced cardiac dysfunction by decreasing OS and apoptosis.
Prophylactic administration of NACA to mice receiving DOX or DOX + TRZ was cardioprotective, with an LVEF of 62% ± 3% and 55% ± 3% on day 10, respectively.
The Canadian journal of cardiology  •  2016  |  View Paper
Accordingly, we determined the ability of NACA to mitigate the cytotoxicity of DOX in H9c2 cells and correlated these effects with the production of indicators of oxidative stress.
BMC pharmacology  •  2009  |  View Paper