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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Doxepin and Epinephrine

drug:

Doxepin

supplement:

Epinephrine

Research Papers that Mention the Interaction

Doxepin potentiates pressor responses to epinephrine , blocks those to tyramine, and at doses above 200mg daily reverses the antihypertensive effects of adrenergic neuron blocking agents like guanethidine and bethanidine.
Drugs  •  1977  |  View Paper
Doxepin potentiated the effect of norepinephrine (NE) on blood pressure and nictitating membrane of cats but reduced the effect of epinephrine (E).
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  •  1972  |  View Paper