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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Taurine also counteracts generation of free radicals, increased release of dopamine , and its metabolism to dihydroxyphenylacetic acid (DOPAC).”
Endogenous neuro-protectants in ammonia toxicity in the central nervous system: facts and hypotheses.“Significantly increased dopamine uptake was detected in the striatal synaptosomes of both WKY and SHR rats fed with low‐dose taurine.”
“Significantly reduced dopamine uptake was detected in the striatal synaptosomes of SHR rats fed with high‐dose taurine.”
Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats“Furthermore, the decreased levels of 5-hydroxytryptamine, dopamine , noradrenaline; the increased levels of glutamate, corticosterone; and the decreased expressions of fibroblast growth factor-2, vascular endothelial growth factor and brain derived neurotrophic factor in depressive rats were hindered by taurine pre-administration.”
“We conclude that the elevations of taurine and dopamine in the nAc are closely related and that in order for ethanol to induce dopamine release, a simultaneous increase of extracellular taurine levels in the nAc is required.”
“In conclusion, our data suggest that extracellular concentrations of dopamine and taurine are interconnected and that swelling of astrocytes contributes to the acute rewarding sensation of EtOH.”
“We conclude that the elevations of taurine and dopamine in the nAc are closely related, and that in order for ethanol to induce dopamine release, a simultaneous increase of extracellular taurine levels in the nAc is required.”
“ Taurine failed to reverse MPTP-induced striatal dopamine depletion, but caused significant increase in dopamine turnover in these animals.”
“At 50 and 150mM taurine elevated dopamine throughout the 4h infusion maximally up to 3–4-fold the control level.”
“The data indicate that taurine , which apparently has to be given intracerebroventricularly in order to reach the brain in sufficient amounts, causes inhibition of firing in central dopamine neurons but has the opposite effect on noradrenaline neurons, perhaps also peripherally, whereas 5-HT neurons appear to be unaffected.”
“We have shown previously that TAU directly inhibits dopamine (DA) and (-)-3-(3,4-dihydroxyphenyl)-L-alanine (L-dopa) oxidation.”
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