Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Dopamine and Sapropterin

supplement:

Sapropterin

Research Papers that Mention the Interaction

On the contrary, when we reduce R-THBP content in the tissues including the brain by use of … tissue content of dopamine and its metabolites very slightly decreased at around 10%, but such a treatment lowering R-THBP … dopamine release ; the dopamine output from the …% of the control level.
This result and other experimental data indicate that the endogenous level of R-THBP can regulate dopamine release.
Advances in experimental medicine and biology  •  1993  |  View Paper
Among various types of pterins, R-THBP has attracted researcher’s interest in recent years, since R-THBP regulates not only the biosynthesis but also the release of biogenic amines such as dopamine and serotonin1,2 and other neurotransmitters, glutamate2 and acetylcholine (ACh)3.
Advances in experimental medicine and biology  •  1993  |  View Paper
Perfusion of 1.0 mM R-THBP enhanced the level of dopamine output in dialysates collected from the striatum and frontal cortex.
These results suggest that R-THBP may play a role in the mechanisms of release of dopamine , serotonin, and glutamate.
Brain Research  •  1991  |  View Paper