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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dopamine
supplement:
Progesterone
Research Papers that Mention the Interaction
“In particular, both estrogen and progesterone have profound effects on the serotonin, norepinephrine, dopamine , and endorphin receptor systems that are involved in mood regulation.”
New perspectives on the relationship of hormone changes to affective disorders in the perimenopause.“ Progesterone further potentiates the effect of estradiol on dopamine release.”
Rapid effects of ovarian hormones in dorsal striatum and nucleus accumbens“Additionally, we found that METH-treatment increased progesterone receptor (PR) immunoreactivity in the MePD, suggesting an interaction between dopamine and progesterone signaling.”
“Thus, taken together, the current findings suggest that dopamine in the MePD modulates enhanced sexual motivation via an amplification of progesterone signaling and contributes to a better understanding of the neurobiology of drug-enhanced sexual behaviors.”
“The DA and D1R agonist increased in vitro release of progesterone and prostaglandin E2 (PGE2) by early CL, whereas the DA and D3R agonist decreased progesterone and increased PGF2α in vitro release by mid- and late CL.”
“ Progesterone added at 1, 10 and 100 nm during stage 4 increased the number of dopamine neurones at stage 5 by 72%, 80% and 62%, respectively, compared to the control group.”
“Intranasal administration of 2 mg/kg of PROG led to an immediate (within 30 min after the treatment) significant increase in the basolateral amygdala dopamine levels.”
“administration of 4 mg/kg of PROG was followed by a delayed significant increase in dopamine , both, in the basolateral amygdala and neostriatum, but smaller in magnitude in comparison to the intranasal treatment.”
“Abstract Objectives: Progesterone modulates dopamine (DA) release in corpus striatum.”
“In previous work we demonstrated that progesterone modulates dopamine release induced by the glutamatergic agonist N-methyl-D-aspartic acid (NMDA).2.”
“One neurotransmitter through which progesterone might regulate many of these functions is dopamine.”
“We found that both progesterone and pregnenolone inhibit [3H]dopamine release in a concentration-dependent manner similarly to prototypical agonists, such as (+)-pentazocine.”
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