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Last Updated: 2 years ago

Possible Interaction: Dopamine and Phenethylamines

supplement:

Phenethylamines

Research Papers that Mention the Interaction

It functions as an activator for the neurotransmission of dopamine and other catecholamines, and very low concentrations of PEA may be associated with specific psychological disorders such as ADHD.
Journal of medicinal food  •  2017  |  View Paper
Platelet monoamine oxidage-B activity is increased by the use of phenylethylamine but decreased by the use of dopamine as substrate.
Neurology  •  1991  |  View Paper
Phenylethylamine administration influences other neurotransmitters such as dopamine , norepinephrine and 5-hydroxytryptamine.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  1984  |  View Paper
Other studies have shown that phenylethylamine is an endogenous precursor-neurotransmitter capable of modulating the activity of dopamine.
Journal of child neurology  •  2014  |  View Paper
These trace amines, including phenethylamine , phenylethanolamine, tyramine and octopamine, are derived from phenylalanine and tyrosine, which are normally metabolized in the liver, and may interfere with neural transmission of noradrenaline and dopamine in the central and peripheral nervous systems [l].
Clinica chimica acta; international journal of clinical chemistry  •  1991  |  View Paper
The phenethylamine derivatives , 4-fluoroamphetamine, 2-methylamino-3,4-methylene-dioxy-propiophenone (methylone), 1-(1,3-benzodioxol-5-yl)-2-butanamine (BDB), and N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine (MBDB), had strong inhibitory effects on the re-uptake of dopamine , 5-HT and norepinephrine.
European journal of pharmacology  •  2007  |  View Paper
It is believed that the locomotor‐stimulating action of β‐PEA , much like amphetamine, depends on its ability to increase extracellular dopamine ( DA ) concentrations owing to reversal of the direction of dopamine transporter (DAT)‐mediated DA transport.
Journal of neurochemistry  •  2004  |  View Paper
DA was released by phenylethylamine at rates significantly greater than its basal rate.
The results suggest (1) that phenylethylamine may exert its behavioural effects through increased release of both DA and 5-HT, and (2) that in vivo measurements of the acid metabolites alone may not be indicative of the release of the amines.
Neurochemical Research  •  2004  |  View Paper
At 7 min, MAO activity towards dopamine was enhanced by 32% and that towards serotonin and phenylethylamine ( PEA ) was decreased by 23 and 25%, respectively.
Pancreas  •  1991  |  View Paper
4 Administration of CEPEA caused more prolonged decreases in brain noradrenaline, dopamine and 5‐hydroxytryptamine concentrations than those observed after PEA administration, although values increased to control levels eventually.
British journal of pharmacology  •  1987  |  View Paper
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