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Last Updated: 4 months ago

Possible Interaction: Dopamine and Phenethylamines

supplement:

Phenethylamines

Research Papers that Mention the Interaction

It functions as an activator for the neurotransmission of dopamine and other catecholamines, and very low concentrations of PEA may be associated with specific psychological disorders such as ADHD.
Journal of medicinal food  •  2017  |  View Paper
Other studies have shown that phenylethylamine is an endogenous precursor-neurotransmitter capable of modulating the activity of dopamine.
Journal of child neurology  •  2014  |  View Paper
At 7 min, MAO activity towards dopamine was enhanced by 32% and that towards serotonin and phenylethylamine ( PEA ) was decreased by 23 and 25%, respectively.
Pancreas  •  1991  |  View Paper
DA was released by phenylethylamine at rates significantly greater than its basal rate.
The results suggest (1) that phenylethylamine may exert its behavioural effects through increased release of both DA and 5-HT, and (2) that in vivo measurements of the acid metabolites alone may not be indicative of the release of the amines.
Neurochemical Research  •  1987  |  View Paper
Combined treatment with phenylethylamine prevented in mice the long-term (30 days post-treatment) dopamine depletions in striatum induced by MPTP.
British journal of pharmacology  •  1985  |  View Paper
Dopamine was released at rates significantly greater than its resting rate by concentrations of phenylethylamine of 5 X 10(-3) to 5 X 10(-5)M; 5 X 10(-6)M phenylethylamine caused a slight increase in release, but the difference from the resting rate was not significant.
The concentrations of phenylethylamine required to increase release of DA in vivo are discussed briefly in relation to the doses required to elicit behavioural effects.
Neuropharmacology  •  1983  |  View Paper
The stabilizable binding of phenylethylamine to calf midbrain (including corpus striatum) homogenates and synaptic membranes was decreased by dopamine ; this amine and D-amphetamine also decreased the stabilizable binding of tyramine to rat brain homogenates.
Research communications in chemical pathology and pharmacology  •  1978  |  View Paper
Administration of [4-T]-β-phenylethylamine, 100 mg kg , showed that the distribution of labelled phenylethylamine in various regions of the brain was significantly correlated with the distribution of dopamine (both in controls and after 100 mg β-phenylethylamine kg ).
An investigation of discrete regions of the brain showed that the same dose of phenylethylamine caused significant depletion of dopamine in the cerebellum, corpus striatum, midbrain, and cortex, but not in the hypothalamus or medulla oblongata-pons region.
Neuropharmacology  •  1973  |  View Paper
Abstract Phenylethylamine decreased the amine content in noradrenaline and dopamine containing nerve terminals in in the brain and in peripheral adrenergic nerve terminals in rats.
European journal of pharmacology  •  1967  |  View Paper