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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Dopamine
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“The liberation of glutamic acid in the striatum is inhibited by dopamine , more specifically by the D2 receptor, which is also though to be responsible for the antipsychotic effects of neuroleptic drugs.”
[A biochemical theory of schizophrenia].“ DA significantly enhanced the Glu uptake in primary cultured astrocyte supernatants.”
[Dopamine inhibits glutamate-uptake ability of astrocytes via TAAR1-EAAT2 pathway].“A possible volumetric interaction between dopamine and glutamic acid as well as the hypothesis of a striato‐pallido‐thalamo‐cortico‐striatal feedback loop are discussed.”
“Adrenaline, dopamine and 5-hydroxytryptamine enhanced fast desensitizing responses of frog spinal motoneurons evoked by L-glutamic acid.”
“ Dopamine (DA) almost completely inhibited the K(+)-evoked release of Asp and Glu in a concentration-dependent manner, but the release of GABA was only partly inhibited.”
“ DA and the selective D-2 receptor agonists quinpirole (LY-171555, the levorotatory enantiomer of LY-141865) and pergolide inhibited GLU release in a concentration-dependent way.”
“The inhibitory effect of DA on the K+-evoked release of GLU was antagonized in a concentration-dependent manner by the selective D-2 receptor antagonist S-sulpiride, but not by the R-enantiomer.”
“In the presence of Ca2+, DA did not significantly alter the effects of L-Glu; however, in the absence of Ca2+ a significant inhibition of the effects of L-Glu by DA was observed.”
“The results indicate that L-GLU provokes regional release of DA by acting at a Mg2+-sensitive glutamate receptor.”
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