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Last Updated: 2 years ago

Possible Interaction: Dopamine and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Based on the facts that prolactin … secretion of the other, that dopamine is the … modulates ACTH release, and finally that alterations of the central dopaminergic tone have been postulated in tumorous hyperprolactinemia, we … dopaminergic system on ACTH and cortisol secretion in patients bearing a prolactinoma and in normal subjects.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology  •  1997  |  View Paper
Similarly, dopamine infusion rates used in man and animals have resulted in plasma concentrations far in excess of those found normally and these pharmacological concentrations have been shown to alter both the clearance rate of exogenous angiotensin II, and the pattern of steroid response to ACTH.
Journal of steroid biochemistry  •  1989  |  View Paper
Also, ACTH may play a role in the regulation of synthesis, release, uptake, and metabolism of a number of neurotransmitters, including dopamine , norepinephrine, serotonin, acetylcholine, and g-aminobutyric acid (GABA) as well as modulate binding at glutamatergic, serotinergic, muscarinic type 1, opiate, and dopaminergic receptors.
Annals of neurology  •  2001  |  View Paper
By manipulating dopamine tone with metoclopramide, bromocriptine, ACTH and amineptine, the aldosterone and prolactin responsiveness was evaluated.
Minerva endocrinologica  •  1992  |  View Paper
In the amenorrheic groups both cortisol and ACTH levels increased significantly (P less than 0.01) after dopamine D-2 receptor blockade, whereas no hormonal changes occurred in the control groups.
Acta endocrinologica  •  1988  |  View Paper
Dopamine (10(-4) M) did not alter the basal secretion of aldosterone, 18-OHB and corticosterone, but suppressed the secretion of these 3 mineralocorticoids by ACTH , which were diminished by addition of 10(-4) M metoclopramide.
Nihon Naibunpi Gakkai zasshi  •  1986  |  View Paper
Dopamine , which does not cross the blood brain barrier, reduced the blood aldosterone response to ACTH ; for those reasons we can hypothesize that receptors D1, stimulated by dopamine modulate aldosterone secretion.
Annales d'endocrinologie  •  1984  |  View Paper
ACTH in the presence of vehicle increased PAC from 8.1 +/- 2.7 to 27.3 +/- 3.1 ng/100 ml; in the presence of dopamine , ACTH increased PAC from 4.7 +/- 0.5 to 34.9 +/- 6.1 ng/100 ml (P = NS).
The Journal of clinical endocrinology and metabolism  •  1982  |  View Paper
In addition, dopamine (10 μM) reduced ACTH secretion during a 4‐h incubation, whereas serotonin (0·01–10 μM) was ineffective.
Clinical endocrinology  •  1981  |  View Paper
Dopamine (0.1 microM) lowered ACTH accumulation in the medium, which was blocked by the addition of haloperidol.
The Journal of clinical investigation  •  1981  |  View Paper
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