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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Dopachrome Isomerase and Ni2+



Research Papers that Mention the Interaction

HPLC analysis … Cu2+, Ni2+ and Co2+ are particularly effective … the non-decarboxylative rearrangement of dopachrome at physiological pH values, leading mainly to 5,6-dihydroxyindole-2-carboxylic acid, whereas in the absence … ions the reaction proceeds with concomitant loss of carbon dioxide to give almost exclusively 5,6-dihydroxyindole.
Biochimica et biophysica acta  •  1987  |  View Paper