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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Domperidone
supplement:
Silymarin
Research Papers that Mention the Interaction
“Conclusions: The significant difference in absorption of domperidone on pretreatment with silymarin is due to the inhibition of P-glycoprotein and CYP3A.”
“ Silymarin , which inhibits CYP3A4, should be contraindicated for domperidone.”
“The silymarin pretreatment increased the bioavailability of domperidone.”
Effect of silymarin pretreatment on the bioavailability of domperidone in healthy human volunteers
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