“Second, using the HRPC CWR22R nude mice model, we found that the combination of SAMC and docetaxel was 53% more potent than docetaxel alone (p = 0.037).”
“These results suggest that SAMC is able to increase the anticancer effect of docetaxel without causing additional toxic effect in vivo.”
“We found that SAMC increased the efficacy of docetaxel on colony forming inhibition by 9–50% compared to single agent treatment.”