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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Docetaxel and Limonene, (+/-)-

Research Papers that Mention the Interaction

Conclusion: Our results show, for the first time, that d-limonene enhanced the antitumor effect of docetaxel against prostate cancer cells without being toxic to normal prostate epithelial cells.
Exposure of DU-145 cells to a combined d-limonene and docetaxel resulted in higher ROS generation, depletion of GSH, accompanied by increased caspase activity than docetaxel alone.
Results: d-Limonene and docetaxel in combination significantly enhanced the cytotoxicity to DU-145 cells than PZ-HPV-7 cells.
We sought to characterize whether a non-toxic dose of d-limonene may enhance tumor response to docetaxel in an in vitro model of metastatic prostate cancer.
Journal of carcinogenesis  •  2009  |  View Paper