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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Docetaxel and Apigenin

supplement:

Apigenin

Research Papers that Mention the Interaction

Moreover, apigenin inhibited not only P-glycoprotein but also BCRP by increasing cellular uptake of doxorubicin and synergistic inhibition of cell viability in combination with doxorubicin or docetaxel in multidrug-resistant cells.
The Journal of nutritional biochemistry  •  2015  |  View Paper
In comparison to oral docetaxel alone (… mg/kg), the bioavailability of docetaxel could be significantly enhanced by 1.6– 2.4‐fold via oral co‐administration with various flavonoids ( apigenin , naringenin, baicalein, quercetin and myricetin) at a dosage of 10 mg/kg, and myricetin showed the highest bioavailability improvement.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2017  |  View Paper