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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Disulfiram
supplement:
Zinc Gluconate
Research Papers that Mention the Interaction
“The combination … oral zinc gluconate … disulfiram at currently approved doses for alcoholism also induced >50% reduction in hepatic metastases and produced clinical remission in a patient with stage … metastatic ocular melanoma, who has continued on oral zinc gluconate and disulfiram therapy for 53 continuous months with negligible side effects.”
Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.
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