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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Disulfiram
supplement:
Epinephrine
Research Papers that Mention the Interaction
“The results obtained from the present study are consistent with previous observations that disulfiram , a dopamine-β-hydroxylase inhibitor, reduces norepinephrine and epinephrine contents in the heart, blood vessels, and adrenal medullae, thereby causing the disturbance in the cardiovascular reflex mechanism.”
“Our results also show that disulfiram can inhibit noradrenaline and adrenaline synthesis in the adrenal glands as it does in the heart and brain.”
Increased uptake of noradrenaline in the rat submaxillary gland during sympathetic nerve stimulation“The results of Goldstein and Nakajima and of Gordon & others, suggest that disulfiram would lower adrenaline levels in the adrenal glands of exercised rats, although inhibitors of catecholamine synthesis produce little change in adrenal adrenaline in normal rats because of its slow turnover.”
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