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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Disopyramide
supplement:
Potassium
Research Papers that Mention the Interaction
“Antiarrhythmic drugs … (quinidine, disopyramide ), class III (sotalol, amiodarone), class IV (calcium … blockers) used at the same time with potassium depleters diuretics or beta-blocking agents result in the inhibition of repolarization and the increased duration … activation potential with the risk of developing arrhythmia of the torsade de pointes types.”
[Unwanted drug interaction between anti-arrhythmic drugs and drugs used for heart failure].“A patient is presented whose electrocardiogram became remarkably abnormal and who developed hypotension while receiving disopyramide and potassium.”
“ External disopyramide at 1.0 mm caused small, poorly reversible inhibition of both sodium and potassium currents.”
The effects of external and internal application of disopyramide on the ionic currents of the squid giant axon
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