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Discover Supplement-Drug Interactions

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Possible Interaction: Disopyramide and Digitalis



Research Papers that Mention the Interaction

The degree of Ca2+ loading is an important determinant of contractility in heart muscle, and therefore alterations in fuzzy space [Na+] may be important in mediating the positive inotropic effects of Na pump inhibitors, such as digitalis , and the negative inotropic effects of Na+ channel blockers such as disopyramide.
Journal of cardiovascular electrophysiology  •  2006  |  View Paper
This therapy may restore sinus rhythm, but conversion to sinus rhythm often requires the combined use of digitalis with a β-blocker or class I antiarrhythmic drug (quinidine, disopyramide , procainamide, propafenone, or flecainide).
Journal of cardiovascular pharmacology  •  1991  |  View Paper