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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Disopyramide
supplement:
Digitalis
Research Papers that Mention the Interaction
“The degree of Ca2+ loading is an important determinant of contractility in heart muscle, and therefore alterations in fuzzy space [Na+] may be important in mediating the positive inotropic effects of Na pump inhibitors, such as digitalis , and the negative inotropic effects of Na+ channel blockers such as disopyramide.”
Na+“Fuzzy Space”: Does It Exist, and Is It Important In Ischemic Injury?“This therapy may restore sinus rhythm, but conversion to sinus rhythm often requires the combined use of digitalis with a β-blocker or class I antiarrhythmic drug (quinidine, disopyramide , procainamide, propafenone, or flecainide).”
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