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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Dipyrone and Hesperidin

supplement:

Hesperidin

Research Papers that Mention the Interaction

The analysis of DRC for the metamizole + hesperidin combination, in a ratio 1:1 showed a ED50 COMB value lower than the ED50 ADD estimated from the additivity line from the isobologram (46.7 ± 6.3 vs. 96.7 ± 11.9 mg/kg, respectively).
These results suggest a synergistic interaction for the antinociceptive activity of metamizole + hesperidin combination.
Archives of medical research  •  2021  |  View Paper