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Possible Interaction: Dipyridamole and Diallyl Trisulfide

Research Papers that Mention the Interaction

After adding DATS (10 and 50 μg/mL) in the everted gut sacs, absorption of dipyridamole was remarkably decreased in the ileum and jejunum (p < 0.01).
After coadministration and long-term pretreatment of DATS , significantly lower Cmax and AUC0–24 h were observed for intragastric administration of dipyridamole , whereas little change was noted after intravenous dipyridamole administration.
…,DATS reduced the … of dipyridamole in rats likely by the modification of the dissolution rate and intestinal absorption of dipyridamole, indicating that combined use of DATS or …-containing supplements with dipyridamole may require caution as low plasma concentrations of dipyridamole may lead to a subtherapeutic effect of this agent.
Archives of pharmacal research  •  2011  |  View Paper