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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Diphenhydramine
supplement:
Sodium Bicarbonate
Research Papers that Mention the Interaction
“ Hypertonic sodium bicarbonate may interact with DPH neuronal sodium channels and may be considered adjuvant therapy in humans with DPH-induced seizures.”
Physostigmine, sodium bicarbonate, or hypertonic saline to treat diphenhydramine toxicity.“While in the emergency department, she manifested a wide-complex tachycardia in the setting of hypotension that required repeated administration of sodium bicarbonate to overcome the sodium channel blockade caused by diphenhydramine.”
A Case of Massive Diphenhydramine and Naproxen Overdose.
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