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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Diosmin and Hesperidin

supplement:

Diosmin

supplement:

Hesperidin

Research Papers that Mention the Interaction

Antihyperalgesic response of hesperidin , improved by a combination with diosmin (DS10/HS100) in both stimuli, was blockaded by haloperidol, bicuculline, and naloxone, but not WAY100635, antagonists.
BioMed research international  •  2016  |  View Paper
In addition, feeding of diosmin and hesperidin , both alone and in combination, significantly inhibited the development of aberrant crypt foci.
These results indicate that diosmin and hesperidin , both alone and in combination, act as a chemopreventive agent against colon carcinogenesis, and such effects may be partly due to suppression of cell proliferation in the colonic crypts, although precise mechanisms should be clarified.
Carcinogenesis  •  1997  |  View Paper
These findings suggest that diosmin and hesperidin supplementation, individually or in combination, is effective in inhibiting the development of oesophageal cancer induced by MNAN when given during the initiation phase, and such inhibition might be related to suppression of increased cell proliferation caused by MNAN in the oesophageal mucosa.
Carcinogenesis  •  1997  |  View Paper