“Therefore, we conclude that intake of DSN or dietary supplements containing DSN may potentially increase the absorption or bioavailability of FEX , a P-gp substrate in humans.”
“Treatment with SN significantly increased the peak maximum plasma concentration (Cmax) and area under the plasma concentration–time curve (AUC) of F EX by 49.2% (523.28 versus 780.63 ng/mL) and 64.4% (3459.48 versus 5687.74 ng h/mL), respectively as compared to control phase.”