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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dinoprostone
supplement:
Turpentine
Research Papers that Mention the Interaction
“We found that febrile response was significantly … in the animals pre-treated with turpentine compared to control rats (pre-treated with saline), and that observed excessive elevation of body temperature (Tb) was accompanied by enhanced release of fever mediators: interleukin-6 (IL-6) and prostaglandin E2 (PGE2) into plasma.”
High mobility group box 1 protein released in the course of aseptic necrosis of tissues sensitizes rats to pyrogenic effects of lipopolysaccharide.“ PGE2 levels (measured in the circulation) were suppressed in both types of KO mice injected with turpentine.”
“Subcellular liver fractions from rats receiving a subcutaneous injection of turpentine , which causes a local inflammation, show an increased synthesis of Prostaglandin E2 and Prostaglandin F2 alpha which reaches a peak 90 minutes and 3 hours after treatment, respectively.”
“In animals fed the control diet, turpentine induced fever, hypermetabolism, marked local inflammation (oedema), increased plasma IL-6 concentrations and raised cerebrospinal fluid (CSF) concentrations of PGE2.”
Dietary n-3 Fatty Acids Inhibit Fever Induced by Inflammation in the Rat
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