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“Additionally, treatment with GT increased the expression of cyclooxygenase‑2 (COX‑2) and the production of prostaglandin E2 (PGE2), as determined by western blot analysis and PGE2 assay.”
“Taken together, these results suggest that tannic acid in HY agent may suppress GIC-induced production of PGE2 by inhibition of COX-2 expression in dental pulp cells.”