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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dinoprostone
supplement:
Myricetin
Research Papers that Mention the Interaction
“ Myricetin dose-dependently suppressed the production of pro-inflammatory mediators (NO, iNOS, PGE2 , and COX-2) in LPS-stimulated RAW264.7 macrophages.”
Anti-inflammatory activity of myricetin from Diospyros lotus through suppression of NF-κB and STAT1 activation and Nrf2-mediated HO-1 induction in lipopolysaccharide-stimulated RAW264.7 macrophages“In addition, myricetin inhibited the content of PGE2 in the peritoneal fluid and platelet aggregation induced by collagen and arachidonic acid in vitro.”
“We found that myricetin significantly downregulated several markers of the neuroinflammatory response in LPS-induced activated microglia, including inducible nitric oxide (NO) synthase (iNOS), cyclooxygenase-2 (COX-2), and proinflammatory modulators and cytokines such as prostaglandin E2 (PGE2), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α).”
Inhibitory Effects of Myricetin on Lipopolysaccharide-Induced Neuroinflammation
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