supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Dinoprostone
supplement:
Hydroxyproline
Research Papers that Mention the Interaction
“ PGE2 decreased nonsignificantly the amounts of hydroxyproline , but the steady-state levels of proα1(I) and proα1(III) collagen chain mRNAs were slightly elevated.”
The effects of interleukin-1 and prostaglandin E2 on accumulation of collagen and steady-state levels of proα1(I) collagen messenger RNA in experimental granulation tissue in rats“Similarly, IL-1 beta decreased hydroxyproline content of granulation tissue seven days postoperatively and PGE2 decreased nonsignificantly the amounts of hydroxyproline but the steady-state levels of pro alpha 1(I) and pro alpha 1(III) collagen chain mRNAs were slightly elevated.”
“IL‐1α (0.1–100 U/ml), 1,25‐(OH)2D3 (1010‐10−7 M), PGE2 (10−9‐10−6 M), and PTH (3 × 10−8‐3 × 10−7 M) dose dependently increased the levels of calcium and hydroxyproline in the medium.”
Menatetrenone inhibits bone resorption partly through inhibition of PGE2 synthesis in vitro
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback