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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Dinoprostone
supplement:
Hesperidin
Research Papers that Mention the Interaction
“ Hesperidin was also found to decrease the level of PGE2 and downregulate the expressions of COX‐2 and VEGF.”
Anti‐carcinogenic effect of hesperidin against renal cell carcinoma by targeting COX‐2/PGE2 pathway in Wistar rats“Treatment with hesperidin suppressed production of PGE2 , nitrogen dioxide (NO2), and expression of iNOS protein.”
“The results demonstrated that hesperidin treatment markedly decreased nitric oxide and prostaglandin E2 production and markedly downregulated inducible nitric oxide synthase and cyclooxygenase-2 expression in IL-1β-stimulated OA chondrocytes.”
Hesperidin protects against IL-1β-induced inflammation in human osteoarthritis chondrocytes.
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