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Possible Interaction: Dinoprostone and Glutathione

supplement:

Glutathione

Research Papers that Mention the Interaction

Hartl D, Starosta V, Maier K, Beck-Speier I, Rebhan C, Becker BF, Latzin P, Fischer R, Ratjen F, Huber RM, et al. Inhaled glutathione decreases PGE2 and increases lymphocytes in cystic fibrosis lungs.
American journal of respiratory and critical care medicine  •  2014  |  View Paper
Inhalation of GSH decreased BALF levels of PGE2 and increased CD4+ and CD8+ lymphocytes in BALF significantly but had no effect on markers of oxidative stress.
We conclude that GSH inhalation in CF patients increases lymphocytes and suppresses PGE2 in the bronchoalveolar space.
Free radical biology & medicine  •  2005  |  View Paper
Addition of glutathione or bicarbonate further increased the production of PGE2.
Prostaglandins  •  1992  |  View Paper
Addition of glutathione (GSH), a coenzyme of PGE2-isomerase, increased PGE2 production 2 to 5-fold during stimulation with anti-IgE. These data support the idea that arachidonic acid metabolites play an important role in modulating the “releasability” of human basophils.
Archives of Dermatological Research  •  1987  |  View Paper
Reduced glutathione GSH ) acted to increase the biosynthesis of PGE2 at the expense of other PGs both in the presence and absence of various cytosols.
Prostaglandins  •  1982  |  View Paper
GSH increased GSH concentration and activities of catalase, glutathione peroxidase and superoxide dismutase in colonic mucosa, and decreased cyclooxygenase-2, prostaglandin E2 and thromboxane B2 levels.
Journal of Gastroenterology  •  2009  |  View Paper
Further, glutathione (GSH) is antagonistic to PGE2 synthesis.
The enhanced NK activity seen with oral GLN supplementation in the tumor-bearing host is associated with GSH mediated suppression of PGE2 synthesis.
The Journal of surgical research  •  1996  |  View Paper
Without oxidant stress, extreme glutathione depletion decreased PGE2 synthesis and caused PGI2 synthesis to exceed PGE2.
The American journal of physiology  •  1994  |  View Paper
These data suggest the possibility that changes in GSH concentration may modulate eicosanoid formation in cells that contain GSH-dependent PGE2 isomerase, as well as either or both prostacyclin or thromboxane synthase(s).
Biochimica et biophysica acta  •  1990  |  View Paper
At a greater GSH concentration, PGE2 synthesis was remarkably enhanced.
The Journal of urology  •  1988  |  View Paper
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