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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dinoprostone
supplement:
Emodin
Research Papers that Mention the Interaction
“ Emodin also significantly decreased the blood levels of COX-2 and PGE2.”
Emodin protects knee joint cartilage in rats through anti-matrix degradation pathway: An in vitro and in vivo study.“Moreover, emodin decreased dramatically the LPS-induced production of NO and PGE2 as well as the protein expression and promoter activity of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2).”
“Comparing with untreated CIA mice, emodin treatment inhibited the levels of TNF-α and IL-6 in the plasma, PGE2 production, and COX-2 protein expression in synovial tissues in a dose manner.”
“Our results demonstrated that aloe-emodin dose-dependently inhibited inducible nitric oxide synthase (iNOS) mRNA expression and nitric oxide (NO) production at 5–40 μM. In addition, the levels of cyclooxygenase-2 (COX-2) mRNA and prostaglandin E2 (PGE2) production were suppressed by 40 μM aloe-emodin.”
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