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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dinoprostone and Eicosatrienoic Acid

Research Papers that Mention the Interaction

Synovial cells incorporated the DGLA, and rIL-… beta-stimulated cells that were incubated with DGLA exhibited a 14-fold increase in PGE1 (to 25.2 +/- ….0 ng/ml, mean +/- SD) and a 70% decrease in PGE2 (to 25.2 +/- 4.2 ng/ml) compared with cells in control medium.
Arthritis and rheumatism  •  1989  |  View Paper
PGE2 synthesis was reduced when DGLA was added to cells (resting or IL-1-stimulated).
Prostaglandins  •  1986  |  View Paper
Feeding the ethyl ester of dihomo-γ-linolenic acid for 25 days to rabbits resulted in increased PGE1 (20to30-fold) and PGE2 (1.5-fold) output by a hormone responsive, in vitro, renal papilla preparation.
Lipids  •  2006  |  View Paper
DHGLA had no effect on the release of 6 keto PGF1 alpha, but inhibited PGE2 and, to a lesser extent, TxB2 synthesis.
European journal of pharmacology  •  1986  |  View Paper