Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a month ago

Possible Interaction: Dinoprostone and Conjugated Linoleic Acid

Research Papers that Mention the Interaction

PGE2 biosynthesis by both cell lines was variably reduced by CLA isomer blend and t10:c12 CLA, but not c9:t11 CLA.
Prostaglandins, leukotrienes, and essential fatty acids  •  2005  |  View Paper
The results obtained show that CLA was found to reduce the production of tumor necrosis factor-α, interleukin (IL)-1β and prostaglandin E2 (PGE2), but had no effect on IL-6 production.
Lipids  •  2012  |  View Paper
Conjugated linoleic acid (CLA) is a polyunsaturated fatty acid that alters the synthesis of PGE2 and reduces the negative effects of TNF on body weight of healthy mice.
Research in nursing & health  •  2005  |  View Paper
Ovalbumin antibody production levels were increased linearly on day 7 after injection of ovalbumin and increased quadratically on day 14 after injection, which follows the increased CLA levels, whereas CLA reduced linearly the production of prostaglandin E2 (PGE2).
Archives of animal nutrition  •  2005  |  View Paper
CONCLUSION CLA reduces renal production of PGE2 , without reduced availability of the precursor fatty acid, AA.
CONCLUSION CLA reduces renal production of PGE2 , without reduced availability of the precursor fatty acid, AA.
Kidney international  •  2003  |  View Paper
Ten days after transplantation, the PGE2 level in the tumor tissue was shown to be depressed in a CLA dose-dependent manner.
Journal of nutritional science and vitaminology  •  2002  |  View Paper
However, dietary CLA decreased mucosal levels of prostaglandin E2 , thromboxane B2 and arachidonic acid in a dose-dependent manner.
The British journal of nutrition  •  2001  |  View Paper
In mice topically treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA), dietary CLA (1.5%) significantly (p < 0.05) reduced PGE2 synthesis (2-fold).
Nutrition and cancer  •  1999  |  View Paper