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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“This positive inotropic effect of PGF2 alpha was not affected by verapamil, but was inhibited by procaine or TMB-8, potent inhibitors of Ca2+ release from intracellular Ca2+ compartments.”
Mobilization of intracellular calcium as a mechanism for the positive inotropic effect by prostaglandin F2 alpha in isolated guinea pig atria.“Caffeine and procaine suppressed the increase in ionic conductance and depolarization produced by noradrenaline or prostaglandin F2alpha.”
“ Procaine suppressed the noradrenaline induced contraction, but accelerated the prostaglandin F2alpha induced contraction.”
“ PGF2alpha (10(-6) g/ml) applied simultaneously with procaine (1.4-2.7 x 10(-3) g/ml) markedly enhanced the mechanical responses of both tissues beyond the effects evoked by PGF2alpha alone.”
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